Target. Fade. Erase.

For stubborn dark spots that refuse to budge, meet your most powerful ally. The NUMBUZIN No.5+ Glutathione TXA Advanced Dark Ampoule Concentrated is a high-potency, targeted brightening treatment formulated with a concentrated dual-active complex of glutathione and tranexamic acid — two of the most clinically effective ingredients for interrupting melanin production and fading deep-set hyperpigmentation. In a compact 10g concentrated format, every drop is precision-engineered to deliver maximum brightening impact where your skin needs it most. This is the treatment for when you mean business.

How to Use

1. Use in your evening routine, after cleansing and toning.
2. Dispense a small amount onto clean fingertips.
3. Apply directly to areas of concern — dark spots, post-acne marks, sun spots, melasma patches — and gently pat until absorbed.
4. Can also be applied across the full face as an intensive brightening treatment.
5. Follow with your regular serum and moisturiser.
6. Always apply SPF 30+ the following morning — essential when targeting hyperpigmentation.
7. Use consistently for 4–8 weeks for visible results on stubborn pigmentation.

Important: As a concentrated active treatment, perform a patch test before first use. Introduce gradually if combining with other actives such as retinol or AHA/BHA.

Tip: Layer under the NUMBUZIN No.5+ Vitamin Glutathione Dark Spot Laser Cream for a complete, targeted brightening routine — the ampoule treats, the cream protects and maintains.

Key Ingredients

• Glutathione — A master antioxidant and melanin-suppressing powerhouse that works at a cellular level to inhibit tyrosinase activity, reduce existing pigmentation, and deliver a whole-face brightening effect that builds with consistent use. Widely used in clinical brightening treatments across Asia.
• Tranexamic Acid (TXA) — A clinically proven brightening active that targets stubborn hyperpigmentation at its source — interrupting the signalling pathway between UV exposure and melanin production to fade melasma, sun spots, and post-inflammatory marks more effectively than vitamin C alone.
• Niacinamide — Blocks the transfer of melanin to skin cells, visibly brightening dark spots and evening skin tone while strengthening the skin barrier and minimising pores — amplifying the brightening effect of glutathione and TXA.
• Vitamin C (Ascorbic Acid) — Inhibits tyrosinase to fade existing dark spots and prevent new ones from forming, while stimulating collagen synthesis for firmer, more radiant skin.
• Sodium Hyaluronate — Delivers deep hydration to keep skin comfortable and plump during the concentrated treatment, preventing any dryness or irritation from the active complex.

Full Ingredient List (INCI)

Water, Glycerin, Niacinamide, Butylene Glycol, Glutathione, Tranexamic Acid, Ascorbic Acid, Sodium Hyaluronate, Panthenol, Allantoin, Adenosine, Centella Asiatica Extract, Camellia Sinensis Leaf Extract, Carbomer, Arginine, 1,2-Hexanediol, Ethylhexylglycerin, Phenoxyethanol, Fragrance.

Formulated without: Parabens · Sulfates · Artificial colourants · Mineral oil

Product Details

• Volume: 10g (concentrated format)
• Skin Type: All skin types, especially hyperpigmentation-prone and uneven skin
• Concern: Stubborn dark spots, melasma, sun spots, post-acne marks, deep-set hyperpigmentation, dullness
• Best used: Evening
• Origin: South Korea